At the Department of Pharmacology of the University of Wyoming, research was conducted on the use of capsaicin (a substance derived from hot peppers) for burning fat in the body of living things. Their conclusion – such a “medicine” can be created, although it does not become a panacea in the matter of extremely fast weight loss. The whole question is how to apply it: with food, in the form of tablets or direct injections.
Capsaicin is known for being responsible for the acute taste of chili peppers, but scientists have determined that it is capable of exciting receptors not only in the mouth of a person. This is about TRPV1, which are stored in large quantities in fat cells and, when activated, they force those to burn energy reserves, rather than accumulate them. However, in pure form, capsaicin is toxic and promises a lot of side effects, therefore, on its basis a working drug “Metabocin” was created.
Studies on fatty mice showed the effectiveness of Metabocin, it promoted weight loss, increased sensitivity to insulin and stimulated the thermogenesis of brown fat. Observations were conducted for eight months in a row and showed no serious abnormalities, the experimental mice steadily lost weight and did not complain about their well-being. Next is the preparation of tests on people, for which scientists are looking for sponsors and, more importantly, volunteers.
The authors of the study caution that a simple introduction to a diet of hot sauces will not help you lose weight. Chili is a good seasoning, but the mechanism of fat burning by itself does not activate it. Moreover, for a greater efficacy, capsaicin and metabolotin are better to be injected directly into adipose tissue in the form of injections, but this is the subject of further research.